A new study shows that medications that have been shown to interact with quetiapine, the generic name for the antipsychotic drug Seroquel, can cause an increase in the risk of dementia. The findings are based on a case-control study of people at high risk of developing Alzheimer's disease.
The study, funded by GlaxoSmithKline's Alzheimer's Drug and Health Research Center in Bethesda, Maryland, is published in the journal "Neurology" and is the first study to show an association between quetiapine and dementia.
Quetiapine, an atypical antipsychotic drug, is approved by the U. S. Food and Drug Administration for the treatment of schizophrenia and bipolar disorder and is known to have some antipsychotic-like properties. It is also sometimes used to treat anxiety disorders and may also be used to treat bipolar disorder in patients who have another mental disorder.
A major concern with the study is that the risk of developing Alzheimer's is greater in people taking quetiapine compared with those taking the drug alone. The risk increases with increasing dosages of the drug, and patients taking quetiapine may have a higher risk of developing Alzheimer's. A similar problem may also be present in people taking the antipsychotic drugs at higher doses than those on the same drug. The risk of Alzheimer's may also increase in people who also have certain other risk factors, such as older age, diabetes or a family history of dementia.
The results were published in the journal Alzheimer's Research Medicine. The research is being presented at the 49th annual meeting of the Association for Research on Ageing, the journal's annual meeting, and in person at GlaxoSmithKline's Alzheimer's Research Center, and will be presented at the American Academy of Neurology's Fall/spring Alzheimer's Conference in Fall 1998.
The study, which is led by Dr. Susan R. Lee, a neuropsychologist and the lead investigator on the study, is based on an earlier phase III study of people who took quetiapine and were at high risk of developing Alzheimer's. The first trial of quetiapine was in the early 1990s when the Food and Drug Administration approved the drug for the treatment of schizophrenia.
The study was led by Dr. Lee's research group, which includes Dr. Charles A. Wicker, and Dr. Thomas A. Beasley, director of the Alzheimer's Disease Research Center at the Cleveland Clinic and former chairman of the National Institute of Mental Health.
The National Institute of Mental Health has been a leading force in research on the relationship between medications and Alzheimer's. In 1996, it helped to establish the Alzheimer's Drug and Health Research Center, which became GlaxoSmithKline's first Alzheimer's Research Center.
It has now helped more than 125,000 people with dementia to learn about their health, including doctors, nurses, and other medical professionals. Researchers are also studying the effects of these medications on people with Alzheimer's.
The study was funded by GlaxoSmithKline, the maker of quetiapine. The research was also funded by a grant from the National Institutes of Health, which is an innovative research-based research center that is focused on the science of the relationship between medications and the development of Alzheimer's disease.
In the study, about one-third of the participants were diagnosed with Alzheimer's disease, compared with about 70 percent of participants in the control group, according to a. The Alzheimer's Drug and Health Research Center has already helped about 50,000 people in their lives to learn about their health and to share information.
The findings also highlight the importance of using a patient's history to guide treatment decisions.
The National Institute on Aging is working with the National Institutes of Health to better understand how medications affect people with Alzheimer's disease and to help the U. Food and Drug Administration and other regulators make the best drug and health care providers available to prevent and treat Alzheimer's disease.
The research is published online March 2, 2004 in the journal Aging. The National Institutes of Health is providing a grant to GlaxoSmithKline to help with the study.
GlaxoSmithKline Ltd.GlaxoSmithKline Pharmaceuticals Inc. has a patent on quetiapine that was granted to the company in 2001.
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Key Features:
Supportful Support:Provide an extended-release tablet that is effective against symptoms of bipolar disorder, schizophrenia, and major depressive disorder.
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The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. For example, any information herein should not be used as a substitute for information provided by a trained healthcare professional. If you have questions about the products listed above, visit our toll-free 24/7 contact your available Fill Day.
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BuSaver is a mental health treatment that helps individuals suffering from bipolar disorder, schizophrenia, depression, or other mental health conditions to alleviate symptoms of depression and anxiety. It contains a variety of support systems that help you reach a therapeutic level. It is suitable for those who are suffering from these conditions, but also may be at risk of taking other medications. It is often used for anxiety and panic disorders.
BuSaver is designed to provide support and treatment for mental health conditions and is suitable for people who suffer from these conditions. It can be used by individuals suffering from bipolar disorder or depression or other mental health conditions, or for individuals who are diagnosed with schizophrenia or bipolar disorder. It is not suitable for individuals suffering from certain mental health conditions, such as mania, hypomania, and bipolar disorder. BuSaver can also be used to support individuals with certain conditions, such as depression, anxiety, and mania.
BuSaver can be used for anxiety but is not suitable for everyone. Individuals may be more susceptible to this medication, and individuals should consult healthcare providers before starting any new medication. It is not suitable for people with certain health conditions such as heart disease, kidney problems, liver problems, or aneurysm.
Seroquel XR (quetiapine fumarate) is an atypical antipsychotic that may be used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. It may be prescribed for the treatment of and bipolar disorder.
Uses
Dosage
The dose of Seroquel XR may vary depending on the indication and the specific symptoms and severity of the condition. It is usually prescribed in the range of 25-150mg per day.
Administration
In most cases, Seroquel XR should be taken orally in the form of a syrup, with or without food.
Take the tablet with a full glass of water.
Missed dose
If you miss a dose of Seroquel XR, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Side effects
The most common side effects of Seroquel XR are drowsiness, dizziness, constipation, nausea, and vomiting. These side effects usually go away on their own within a few days. However, if you experience any of these symptoms or if they bother you, it is important to consult your doctor.
Interactions
Seroquel XR may interact with certain medications and supplements. It is important to inform your doctor about all the medications you are taking, including over-the-counter medications, vitamins and herbal supplements, and even prescription and over-the-counter drugs. It is always best to discuss any existing medical conditions or allergies with your doctor before starting this medication.
Drug Interactions
Storage
Store Seroquel XR at room temperature, away from moisture and heat. Keep the tablets out of reach of children and pets.
Precautions
Seroquel XR may be used for the treatment of schizophrenia and bipolar disorder. It is important to inform your doctor about all the medications you are taking, including over-the-counter medications, vitamins and herbal supplements.
They usually go away on their own within a few days.
Seroquel 25mg tablets are a trusted ally in the treatment of mental health conditions such as schizophrenia, bipolar disorder, and major depressive disorder. Each box contains 60 small, easy-to-swallow tablets, offering relief and support for over a month's supply. Key Features: - Effective Support: Designed to alleviate symptoms of schizophrenia and bipolar disorder, helping you regain stability and joy in your everyday life. - Antipsychotic Medication: Part of the renowned class of atypical antipsychotics, providing a modern approach to mental health management. - Convenient Dosing: 25mg tablets offer flexibility in dosing adjustments as prescribed by healthcare professionals. - Trusted Solution: Backed by extensive research and clinical use, ensuring safe and effective treatment options. Usage Instructions: - Dosage: Follow the instructions provided by your healthcare provider, ensuring accurate and beneficial use. - Storage: Store the tablets at room temperature, away from moisture and direct sunlight, to maintain their effectiveness. Warnings and Precautions: - Always take Seroquel under the supervision of a healthcare professional to avoid any adverse effects or interactions. - Not recommended for use in elderly patients with dementia-related psychosis due to increased risk of death. Seroquel is more than just a medication; it's a stepping stone towards better mental health and emotional balance. With the convenience of having 60 tablets at your disposal, managing your mental health condition with consistency and care has never been easier. Remember, always consult with your healthcare provider to ensure it’s the right fit for your treatment plan.
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